In 1997 Mpho was introduced to the music programme at the Mofolo Arts Centre, and it was here that she first learnt to play the djembe drum. In 2001 she joined the Drum Cafe and she has spent the last seven years focusing on drumming technique. She also performs with Basadi Le Meropa, and has done numerous international tours with the group, including a trip to Holland, where she performed at the Mundial festival. In 2006 she joined the cast of Drumstruck in New York and performed in the show for five months.